PANews reported on May 22 that, according to Cointelegraph, the Coinbase premium, a key metric for measuring institutional participation in the crypto market, has fallen into deeper negative territory, indicating increased institutional selling pressure. The premium has been mostly negative since the end of April, accelerating its decline over the past seven days, reaching a monthly low of -0.0983% on May 21. CryptoQuant analyst Darkfost stated that the recent intensification of institutional selling pressure suggests that institutional and professional investors trading on Coinbase Advanced are selling more aggressively than those on Binance. Since May 14, US spot Bitcoin ETFs have seen net outflows for four consecutive trading days, totaling $1.3 billion. Open interest in Bitcoin futures and perpetual contracts has decreased by approximately $1.5 billion this week. Bitcoin has fallen 4.5% over the past week, hitting a monthly low above $76,000 on Tuesday.